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Immunogen sequence: VPEWTKCSNR EKRKEKEKPF YSDSEGESGP TESADSDPES ESESDSKSSS ESGSGESSSE SDNEDQ
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: adapter-related protein complex 3 subunit beta-2; Adaptor protein complex AP-3 subunit beta-2; adaptor related protein complex 3, beta 2 subunit; Adaptor-related protein complex 3 subunit beta-2; adaptor-related protein complex 3, beta 2 subunit; AP-3 complex subunit beta-2; ap3; Beta-3B-adaptin; Clathrin a; Clathrin assembly protein complex 3 beta-2 large chain; Neuron-specific vesicle coat protein beta-NAP; Neuronal adaptin-like protein, beta-subunit
基因别名: AP3B2; NAPTB
UniProt ID: (Human) Q13367
Entrez Gene ID: (Human) 8120