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AP3S2 (Adaptor Related Protein Complex 3 Subunit Sigma 2) is a Protein Coding gene. Among its related pathways are Lysosome. Gene Ontology (GO) annotations related to this gene include protein transporter activity. An important paralog of this gene is AP3S1. Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: adapter-related protein complex 3 subunit sigma-2; adaptor complex sigma3B; adaptor related protein complex 3, sigma 2 subunit; Adaptor-related protein complex 3 subunit sigma-2; adaptor-related protein complex 3, sigma 2 subunit; AP-3 complex subunit sigma-2; AP-3 complex subunit sigma-3B; clathrin-associated/assembly/adaptor protein, small 4, 22-kD; FLJ35955; Sigma-3B-adaptin; Sigma-adaptin 3b; Sigma3B-adaptin
基因别名: AP3S2; AP3S3; sigma3b
UniProt ID: (Human) P59780
Entrez Gene ID: (Human) 10239