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APITD1 Antibody (PA5-104352) in IHC (P)
Immunohistochemistry analysis of APITD1 in rat colorectal tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with APITD1 polyclonal antibody (Product # PA5-104352) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-104352
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CENPS(Accession Q8N2Z9), corresponding to amino acid residues K99-N138.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853662
产品详细信息
Antibody detects endogenous levels of total CENPS.
靶标信息
APITD1 was identified in the neuroblastoma tumour suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumours, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Apoptosis-inducing TAF9-like domain-containing protein 1; Apoptosis-inducing TAF9-like domain-containing protein 1 homolog; CENP-S; Centromere protein S; FANCM-associated histone fold protein 1; FANCM-interacting histone fold protein 1; Fanconi anemia-associated polypeptide of 16 kDa; ortholog of human apoptosis-inducing, TAF9-like domain 1 APITD1
基因别名: 2610040C18Rik; 2810407L01Rik; APITD1; CENP-S; CENPS; FAAP16; MHF1
UniProt ID: (Human) Q8N2Z9, (Mouse) Q9D084
Entrez Gene ID: (Human) 378708, (Mouse) 69928, (Rat) 100534597
resolution of meiotic recombination intermediates
DNA repair
mitotic recombination
cellular response to DNA damage stimulus
sister chromatid cohesion
mitotic nuclear division
replication fork processing
positive regulation of protein ubiquitination
CENP-A containing nucleosome assembly
interstrand cross-link repair
cell division
kinetochore assembly
cell cycle
pentose-phosphate shunt
oxidation-reduction process
