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APOBEC2 Antibody (PA5-116874) in WB
Western blot analysis of APOBEC2 in extracts of various cell lines. Samples were incubated with APOBEC2 Polyclonal antibody (Product # PA5-116874) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-116874
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human APOBEC2 (NP_0067801)
偶联物
形式
Liquid
浓度
2.56 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901505
产品详细信息
Positive Samples: Mouse heart, Mouse skeletal muscle, Rat heart
Immunogen sequence: MAQKEEAAVA TEAASQNGED LENLDDPEKL KELIELPPFE IVTGERLPAN FFKFQFRNVE YSSGRNKTFL CYVVEAQGKG GQVQASRGYL EDEHAAAHAE EAFFNTILPA FDPALRYNVT WYVSSSPCAA CADRIIKTLS KTKNLRLLIL VGRLFMWEEP EIQAALKKLK EAGCKLRIMK PQDFEYVWQN FVEQEEGESK AFQPWEDIQE NFLYYEEKLA DILK
靶标信息
APOBEC2 belongs to the cytidine and deoxycytidylate deaminase family. It is probable C to U editing enzyme whose physiological substrate is not yet known. It does not display detectable apoB mRNA editing and has a low intrinsic cytidine deaminase activity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apolipoprotein B editing complex 2; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 2; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2; C->U-editing enzyme APOBEC-2; mRNA(cytosine(6666)) deaminase 2; OTTHUMP00000039773; probable C->U-editing enzyme APOBEC-2
基因别名: APOBEC2; ARCD1; ARP1
UniProt ID: (Human) Q9Y235, (Mouse) Q9WV35
Entrez Gene ID: (Human) 10930, (Rat) 301226, (Mouse) 11811
RNA binding
cytidine deaminase activity
zinc ion binding
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
catalytic activity
GTP cyclohydrolase activity
tRNA-specific adenosine deaminase activity
hydrolase activity
N-cyclopropylmelamine deaminase activity
N-cyclopropylammeline deaminase activity
N-cyclopropylammelide alkylamino hydrolase activity
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity
tRNA-specific adenosine-37 deaminase activity
archaeal-specific GTP cyclohydrolase activity
metal ion binding
tRNA-specific adenosine-34 deaminase activity
RNA processing factor
