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APOBEC3A Antibody (PA5-142329) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of APOBEC3A in A549 cells using APOBEC3A Polyclonal Antibody (Product # PA5-142329). Cells were fixed with paraformaldehyde, permeabilized with 0.15% Triton, and incubated with the primary antibody for 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing nuclear and some cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL).
产品信息
PA5-142329
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-TSNFNNGIGRHKTY (aa 19-32).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2932980
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
靶标信息
PHO1 a member of the cytidine deaminase gene family. The PHO1 gene is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. This gene encodes a protein that lacks the zinc binding activity and may be an expressed pseudogene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A3A; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3A; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A; DNA dC->dU-editing enzyme APOBEC-3A; PHO-1; pho1; phorbolin 1; Phorbolin-1; Phorbolin1; probable DNA dC->dU-editing enzyme APOBEC-3A
基因别名: A3A; APOBEC3A; ARP3; bK150C2.1; PHRBN
UniProt ID: (Human) P31941
Entrez Gene ID: (Human) 200315
cytidine deamination
negative regulation of transposition
clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine
negative regulation of viral genome replication
innate immune response
defense response to virus
DNA cytosine deamination
cellular response to xenobiotic stimulus
DNA demethylation
