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产品信息
PA5-31132
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein fragment corresponding to a region within amino acids 34 and 263 of Human APOBEC3F
偶联物
形式
Liquid
浓度
0.69 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548606
产品详细信息
Recommended positive controls: Jurkat.
Predicted reactivity: Human (98%), Rhesus Monkey (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This protein is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A3F; apolipoprotein B editing enzyme catalytic polypeptide-like 3F; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3F; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F; DNA dC->dU-editing enzyme APOBEC-3F; induced upon T-cell activation
基因别名: A3F; APOBEC3F; ARP8; BK150C2.4.MRNA; KA6
UniProt ID: (Human) Q8IUX4
Entrez Gene ID: (Human) 200316
positive regulation of defense response to virus by host
cytidine deamination
negative regulation of transposition
base conversion or substitution editing
negative regulation of viral genome replication
innate immune response
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
negative regulation of viral process
defense response to virus
DNA cytosine deamination
DNA demethylation
