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This antibody detects endogenous protein at a molecular weight of 152 kDa.
Purity is >95% by SDS-PAGE.
This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Rho guanine nucleotide exchange factor (GEF) 10; Rho guanine nucleotide exchange factor 10
基因别名: 6430549H08Rik; ARHGEF10; GEF10; KIAA0294; mKIAA0294; RGD1565043; SNCV
UniProt ID: (Human) O15013, (Mouse) Q8C033
Entrez Gene ID: (Human) 9639, (Mouse) 234094, (Rat) 306618