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Immunogen sequence: GTAHTEAQQS FMSPSSSCAS NLNLSFGWHG FEKEQSHLKK RSSSLDALDA DSEGEGHSEP SHICYTPGSQ SSSRTGIPSG DELDSFETNT EPDFNI
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 74%.
This gene encodes a member of the Rho guanine nucleotide exchange factor family. The encoded protein interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 190 kDa guanine nucleotide exchange factor; p190-RhoGEF; Rho guanine nucleotide exchange factor; Rho guanine nucleotide exchange factor (GEF) 28; Rho guanine nucleotide exchange factor 28; Rho interacting protein 2; rho-guanine nucleotide exchange factor
基因别名: ARHGEF28; KIAA1998; p190RHOGEF; RGNEF; RIP2
UniProt ID: (Human) Q8N1W1
Entrez Gene ID: (Human) 64283