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产品信息
H00007984-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3A12-B5
抗原
ARHGEF5 (AAH14555, 1 a.a. approximately 519 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: MGGFSRRCSK LINSSQLLYQ EYSDVVLNKE IQSQQRLESL SETPGPSSPR QPRKALVSSE SYLQRLSMAS SGSLWQEIPV VRNSTVLLSM THEDQKLQEV KFELIVSEAS YLRSLNIAVD HFQLSTSLRA TLSNQEHQWL FSRLQDVRDV SATFLSDLEE NFENNIFSFQ VCDVVLNHAP DFRRVYLPYV TNQTYQERTF QSLMNSNSNF REVLEKLESD PVCQRLSLKS FLILPFQRIT RLKLLLQNIL KRTQPGSSEE AEATKAHHAL EQLIRDCNNN VQSMRRTEEL IYLSQKIEFE CKIFPLISQS RWLVKSGELT ALEFSASPGL RRKLNTRPVH LHLFNDCLLL SRPREGSRFL VFDHAPFSSI RGEKCEMKLH GPHKNLFRLF LRQNTQGAQA EFLFRTETQS EKLRWISALA MPREELDLLE CYNSPQVQCL RAYKPRENDE LALEKADVVM VTQQSSDGWL EGVRLSDGER GWFPVQQVEF ISNPEVRAQN LKEAHRVKTA KLQLVEQQA
靶标信息
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARH5; DKFZp686N1969; Ephexin 3; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; p60 TIM; Rho guanine nucleotide exchange factor (GEF) 5; Rho guanine nucleotide exchange factor 5; Transforming immortalized mammary oncogene
基因别名: ARHGEF5; GEF5; P60; TIM; TIM1
UniProt ID: (Human) Q12774
Entrez Gene ID: (Human) 7984
myeloid dendritic cell chemotaxis
actin cytoskeleton organization
regulation of actin cytoskeleton organization
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of GTPase activity
positive regulation of JUN kinase activity
positive regulation of GTPase activity
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
positive regulation of stress fiber assembly
regulation of ERK1 and ERK2 cascade
positive regulation of podosome assembly
positive regulation of protein import
