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ASC1 Antibody (MA5-50797) in IHC (P)
Immunohistochemistry of ASC1 in paraffin-embedded rat small intestine tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with ASC1 recombinant monoclonal antibody (Product # MA5-50797) with a dilution of 1:200 for 1 hour a... View More
产品信息
MA5-50797
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH0-26
抗原
Recombinant protein within human ASC1 aa 1-581/581.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3092432
产品详细信息
Positive control: A549 cell lysate, Hela cell lysate, U87-MG cell lysate, 293T cell lysate, HL-60 cell lysate, HepG2 cell lysate, RH-35 cell lysate, rat small intestine tissue.
Predicted band size: 66 kDa
Subcellular Location: Nucleus, Cytoplasm, cytosol, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
靶标信息
Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; zinc finger, C2HC5-type
基因别名: ASC-1; ASC1; HsT17391; RQT4; SMABF1; TRIP4; ZC2HC5
UniProt ID: (Human) Q15650
Entrez Gene ID: (Human) 9325, (Rat) 315769
