Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
A301-749A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 2919 and 2969 of human absent, small and homeotic disks protein 1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
靶标信息
ASH1 (ASH1L) is a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. Diseases associated with ASH1 include Mental Retardation, Autosomal Dominant 52 and Pulpitis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Absent small and homeotic disks protein 1 homolog; absent, small, or homeotic discs 1; ash1 (absent, small, or homeotic)-like; ASH1-like protein; chromatin remodeling factor; Histone-lysine N-methyltransferase ASH1L; huASH1; Lysine N-methyltransferase 2H; probable histone-lysine N-methyltransferase ASH1L
基因别名: 8030453L17Rik; ASH1; ASH1L; ASH1L1; E430018P19Rik; KIAA1420; KMT2H
UniProt ID: (Human) Q9NR48, (Mouse) Q99MY8
Entrez Gene ID: (Human) 55870, (Mouse) 192195
DNA binding
chromatin binding
zinc ion binding
histone methyltransferase activity (H3-K4 specific)
histone methyltransferase activity (H3-K36 specific)
methyltransferase activity
transferase activity
histone-lysine N-methyltransferase activity
metal ion binding
chromatin/chromatin-binding, or -regulatory protein
histone modifying enzyme
negative regulation of acute inflammatory response
DNA packaging
transcription from RNA polymerase II promoter
cell-cell signaling
interleukin-6 production
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of MAPK cascade
positive regulation of transcription from RNA polymerase II promoter
histone H3-K4 methylation
histone H3-K36 dimethylation
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
methylation
negative regulation of inflammatory response
