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产品信息
H00055870-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4G12
抗原
ASH1L (NP_060959.1, 2859 a.a. approximately 2967 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: DALPLIEEVL ASQEQAANEI PSLEEPEREG ATANVSEGEK KTEESSQEPQ STCTPEERRH NQRERLNQIL LNLLEKIPGK NAIDVTYLLE EGSGRKLRRR TLFIPENSF
靶标信息
ASH1 (ASH1L) is a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. Diseases associated with ASH1 include Mental Retardation, Autosomal Dominant 52 and Pulpitis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Absent small and homeotic disks protein 1 homolog; ash1 (absent, small, or homeotic)-like; ASH1-like protein; Histone-lysine N-methyltransferase ASH1L; huASH1; Lysine N-methyltransferase 2H; probable histone-lysine N-methyltransferase ASH1L
基因别名: ASH1; ASH1L; ASH1L1; KIAA1420; KMT2H
UniProt ID: (Human) Q9NR48
Entrez Gene ID: (Human) 55870
negative regulation of acute inflammatory response
DNA packaging
transcription from RNA polymerase II promoter
cell-cell signaling
interleukin-6 production
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of MAPK cascade
positive regulation of transcription from RNA polymerase II promoter
histone H3-K4 methylation
histone H3-K36 dimethylation
