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产品信息
H00000444-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ASPH (AAH25236.1, 1 a.a. approximately 270 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.35 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHETEHSYH VEETVSQDCN QDMEEMMSEQ ENPDSSEPVV EDERLHHDTD DVTYQVYEEQ AVYEPLENEG IEITEVTAPP EDNPVEDSQV IVEEVSIFPV EEQQEVPPDT
靶标信息
ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins. This gene is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.
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生物信息学
蛋白别名: A beta H-J-J; ASP beta-hydroxylase; Aspartate beta-hydroxylase; Aspartyl/asparaginyl beta-hydroxylase; aspartyl/asparaginyl-beta-hydroxylase; cardiac junctin; humbug; junctate; Peptide-aspartate beta-dioxygenase
基因别名: AAH; ASPH; BAH; CASQ2BP1; FDLAB; HAAH; JCTN; junctin
UniProt ID: (Human) Q12797
Entrez Gene ID: (Human) 444
muscle contraction
pattern specification process
negative regulation of cell proliferation
regulation of protein stability
ion transmembrane transport
limb morphogenesis
peptidyl-aspartic acid hydroxylation
positive regulation of proteolysis
oxidation-reduction process
palate development
face morphogenesis
activation of cysteine-type endopeptidase activity
regulation of protein depolymerization
regulation of cardiac conduction
