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Immunogen sequence: SHLPKEIVFA NSMGKGYYLK GKIGKVPVRF LVDSGAQVSV VHPNLWEEVT DGDLDTLQPF ENVVKVANGA EMKILGVWDT AVSL
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 25%.
Filaggrin is a structural protein that is crucial for in the development and maintenance of the skin barrier. This gene encodes a retroviral-like protease involved in profilaggrin-to-filaggrin processing. Expression is found primarily in the epidermis and inner root sheath of hair follicles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ASPRV1; Retroviral-like aspartic protease 1; SASPase; skin aspartic protease; Skin-specific retroviral-like aspartic protease; TAPS; TPA-inducible aspartic proteinase-like protein
Gene Aliases: ASPRV1; MUNO; SASP; SASPase; Taps
UniProt ID: (Human) Q53RT3
Entrez Gene ID: (Human) 151516
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