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ATG4A Antibody (PA5-116489) in IHC (P)
Immunohistochemical analysis of ATG4A in a paraffin-embedded human placenta tissue using a ATG4A polyclonal antibody (Product #PA5-116489). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (1:50) for 30... View More
产品信息
PA5-116489
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within Human ATG4A aa 87-314
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2901120
产品详细信息
Positive controls: Human placenta tissue, mouse testis tissue, rat bone marrow.
靶标信息
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: APG4 (ATG4) autophagy-related homolog A; APG4 autophagy 4 homolog A; ATG4 autophagy related 4 homolog A; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; autophagin 2; Autophagin-2; autophagy 4 homolog A; autophagy related 4 homolog A; autophagy related 4A, cysteine peptidase; autophagy-related 4A; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; cysteine protease APG4A; Cysteine protease ATG4A; hAPG4A; HsAPG4A; MGC107179
基因别名: AI627006; APG4A; ATG4A; Atg4al; AUTL2; AV169859
UniProt ID: (Human) Q8WYN0, (Mouse) Q8C9S8
Entrez Gene ID: (Human) 115201, (Mouse) 666468, (Rat) 678769
