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Immunogen sequence: IPWLLSPESL DIKEINGNKI TCRGLVEYFK AYIKIYQGEE LPHPKSMLQA TAEANNLAAV ATAKDTYNKK MEEICGGDKP FLAPNDLQTK HLQLKEESVK LFRGVKKMGG EEFSRRYLQQ LESE
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.
The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATL1 alpha; ATL1 beta; ATL1 gamma; ATL1-delta; Atlastin-1; BCL-11B; Bcl11B; BCL11B/TRDC fusion; Brain-specific GTP-binding protein; Ctip 2; CTIP-2; CTIP2; GBP-3; GTP-binding protein 3; Guanine nucleotide-binding protein 3; guanylate-binding protein 3; hGBP3; hRit1; hRIT1 alpha; Rit 1; Rit1; Spastic paraplegia 3 protein A; ZNF856B
基因别名: AD-FSP; ATL1; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A
UniProt ID: (Human) Q8WXF7
Entrez Gene ID: (Human) 51062