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产品信息
PA5-88526
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 65-240 of human ATP1B1 (NP_0016681)
偶联物
形式
Liquid
浓度
2.59 mg/mL
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804976
产品详细信息
Immunogen sequence: KPTYQDRVAP PGLTQIPQIQ KTEISFRPND PKSYEAYVLN IVRFLEKYKD SAQRDDMIFE DCGDVPSEPK ERGDFNHERG ERKVCRFKLE WLGNCSGLND ETYGYKEGKP CIIIKLNRVL GFKPKPPKNE SLETYPVMKY NPNVLPVQCT GKRDEDKDKV GNVEYFGLGN SPGFPL; Positive Samples: U-251MG, Mouse brain, Mouse liver, Mouse kidney, Rat kidney, Rat brain; Cellular Location: Cell membrane, Single-pass type II membrane protein
靶标信息
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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