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ATP4B Antibody (MA5-42699) in IHC (P)
Immunohistochemistry analysis of ATP4B in paraffin-embedded mouse stomach. Samples were incubated with ATP4B Monoclonal antibody (Product # MA5-42699) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
产品信息
MA5-42699
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3Y1Y1
抗原
A synthetic peptide corresponding to a sequence within amino acids 192-291 of human ATP4B (P51164).
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2911840
产品详细信息
Positive test controls include: HT-29, HepG2, Mouse stomach, Rat testis. The target is usually found in the following locations: Cell membrane, Single-pass type II membrane protein.
Immunogen sequence: SNGSAPRVDC AFLDQPRELG QPLQVKYYPP NGTFSLHYFP YYGKKAQPHY SNPLVAAKLL NIPRNAEVAI VCKVMAEHVT FNNPHDPYEG KVEFKLKIEK
靶标信息
The hydrogen/potassium ATPase, or gastric proton pump, belongs to a family of P-type cation-transporting ATPases. This family of ATPases shares a number of functional and structural similarities including the common feature of consisting of an alpha and beta subunit. Like the ubiquitous sodium/potassium ATPase, the hydrogen/potassium ATPase consists of a large transmembrane catalytic subunit, termed the alpha- subunit which contains sites for ATP binding and phosphorylation, and an associated smaller glycoprotein, termed the beta-subunit which may play a role in maintaining the structural and functional integrity of the complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATPase H+K+-transporting beta / (gastric HK-ATPase beta subunit) defined by SSR; ATPase, H+,K+-transporting, beta / (gastric H,K-ATPase beta subunit), defined by SSR; ATPase, H+/K+ exchanging, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide, gastric specific; Gastric H(+)/K(+) ATPase subunit beta; gastric H+/K+ ATPase beta subunit; gastric hydrogen-potassium ATPase, beta; H+,K+-ATPase; H+/K+ ATPase beta; H+/K+-ATPase beta; H,K-ATPase-Beta; potassium-transporting ATPase beta chain; Potassium-transporting ATPase subunit beta; Proton pump beta chain
基因别名: ATP4B; ATP6B; AV080843; S76401S1
UniProt ID: (Human) P51164, (Rat) P18598, (Mouse) P50992
Entrez Gene ID: (Human) 496, (Rat) 24217, (Mouse) 11945
potassium ion transport
sodium ion transport
cell adhesion
response to organonitrogen compound
response to lipopolysaccharide
ion transmembrane transport
hydrogen ion transmembrane transport
gastric acid secretion
transport
ion transport
regulation of proton transport
proton transport
protein glycosylation in endoplasmic reticulum
pH reduction
potassium ion transmembrane transport
