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产品信息
PA5-60665
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2638372
产品详细信息
Immunogen sequence: EVKRCEELER ILVYLVQEIN RADIPLPEGE ASPPAPPLKQ VLEMQEQLQK LEVELREVTK NKEKLRKNLL ELIEYTHMLR VTKTFVKRNV EFEPTYEEFP SLESDSLLDY SCMQRLGAKL GFVSGLINQG KVEAFE
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%.
靶标信息
The multisubunit vacuolar-type proton pump (H(+)-ATPase or V-ATPase) is essential for acidification of diverse cellular components, including endosomes, lysosomes, clathrin-coated vesicles, secretory vesicles, and chromaffin granules, and it is found at high density in the plasma membrane of certain specialized cells. H(+)-ATPases are comprised of a peripheral V(1) domain and an integral membrane V(0) domain; ATP6V0A2 is a component of the V(0) domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A2V-ATPase; ATP6 ATP6N1D; ATPase, H+ transporting, lysosomal V0 subunit a2; Lysosomal H(+)-transporting ATPase V0 subunit a 2; lysosomal H(+)-transporting ATPase V0 subunit a2; regeneration and tolerance factor; TJ6; v-ATPase 116 kDa; V-ATPase 116 kDa subunit a 2; v-type proton ATPase 116 kDa subunit a; V-type proton ATPase 116 kDa subunit a 2; vacuolar proton translocating ATPase 116 kDa subunit a; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2
基因别名: A2; ARCL; ARCL2A; ATP6A2; ATP6N1D; ATP6V0A2; J6B7; RTF; STV1; TJ6; TJ6M; TJ6S; VPH1; WSS
UniProt ID: (Human) Q9Y487
Entrez Gene ID: (Human) 23545
immune response
vacuolar acidification
insulin receptor signaling pathway
ATP synthesis coupled proton transport
ATP hydrolysis coupled proton transport
regulation of macroautophagy
transferrin transport
ion transmembrane transport
vacuolar proton-transporting V-type ATPase complex assembly
phagosome acidification
