Invitrogen

ATP6V0D2 Polyclonal Antibody

3 Published Figures

4 References

View all (9) ATP6V0D2 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)
Published Figures (3)

FIGURE: 1 / 4

ATP6V0D2 Antibody (PA5-44359) in WB

Western blot analysis of transfected 293T cells using an anti-ATP6V0D2 polyclonal antibody (Product # PA5-44359).

ATP6V0D2 Antibody in Immunocytochemistry (ICC/IF)

Product Image Gallery

Product Details

PA5-44359

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1 µg/mL

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the middle region of human ATP6V0D2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

AB_2606627

Product Specific Information

Peptide sequence: GLRLLAQAED FDQMKNVADH YGVYKPLFEA VGGSGGKTLE DVFYEREVQM

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Target Information

ATP6V0D2 is the subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. ATP6V0D2 may play a role in coupling of proton transport and ATP hydrolysis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins.

Nature communications

Place DE,Malireddi RKS,Kim J,Vogel P,Yamamoto M,Kanneganti TD

PA5-44359 was used in Western Blotting to investigate the effects of reduced IFN signalling components on bone density and osteoclasyogenesis in mice.

Thu Jan 21 00:00:00 UTC 2021

A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.

Cell proliferation

Yan K,Wu C,Ye Y,Li L,Wang X,He W,Ren S,Xu Y

PA5-44359 was used in Western Blot to suggest that A20 may be a key gene target during bone loss in periodontitis via TRAF6-mediated inhibition of autophagy.

Sun Mar 01 00:00:00 UTC 2020

A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.

Cell proliferation

Yan K,Wu C,Ye Y,Li L,Wang X,He W,Ren S,Xu Y

PA5-44359 was used in Western Blot to suggest that A20 may be a key gene target during bone loss in periodontitis via TRAF6-mediated inhibition of autophagy.

Sun Mar 01 00:00:00 UTC 2020

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.

Nature

Montoro DT,Haber AL,Biton M,Vinarsky V,Lin B,Birket SE,Yuan F,Chen S,Leung HM,Villoria J,Rogel N,Burgin G,Tsankov AM,Waghray A,Slyper M,Waldman J,Nguyen L,Dionne D,Rozenblatt-Rosen O,Tata PR,Mou H,Shivaraju M,Bihler H,Mense M,Tearney GJ,Rowe SM,Engelhardt JF,Regev A,Rajagopal J

PA5-44359 was used in Immunohistochemistry-immunofluorescence to combine single-cell RNA-seq and in vivo lineage tracing to study the cellular composition and hierarchy of the murine tracheal epithelium.

Wed Aug 01 00:00:00 UTC 2018

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.

Nature

Wed Aug 01 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; FLJ38708; V-ATPase subunit d 2; V-type proton ATPase subunit d 2; Vacuolar proton pump subunit d 2

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Gene Aliases: ATP6D2; ATP6V0D2; VMA6

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UniProt ID: (Human) Q8N8Y2

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Entrez Gene ID: (Human) 245972

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Function(s)

protein binding hydrogen ion transmembrane transporter activity ATP synthase

Process(es)

insulin receptor signaling pathway ATP hydrolysis coupled proton transport regulation of macroautophagy transferrin transport ion transmembrane transport phagosome acidification

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ATP6V0D2 Polyclonal Antibody

ATP6V0D2 Antibody (PA5-44359) in WB

Product Details

PA5-44359

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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