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ATP7B Antibody (PA5-122222) in IHC (P)
Immunohistochemistry of ATP7B in paraffin-embedded human kidney tissue. Samples were incubated in polyclonal ATP7B antibody (Product # PA5-122222) using a dilution of 10 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG at a dilution of 2 µg/mL and DAB.
产品信息
PA5-122222
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Thr59-Val426 (Accession P35670), with N-terminal His Tag
偶联物
形式
Liquid
浓度
0.76 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2915794
靶标信息
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; Copper pump 2; Copper-transporting ATPase 2; RP11-327P2.1; RP11-327P2.3; Wilson disease-associated protein
基因别名: ATP7B; PWD; WC1; WD; WND
UniProt ID: (Human) P35670
Entrez Gene ID: (Human) 540
