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AVPR1A Antibody (711640) in ICC/IF
HEK 293 cells stably transfected with Vasopressin Receptor 1A (AVPR1A) were grown on poly-L-lysine-coated coverslips overnight. After 24 h, cells were fixed with 4% paraformaldehyde and 0.2% picric acid in phosphate buffer (pH 6.9) for 30 min at room temperature and washed several times with phosphate buffer. Specimens were permeabilized with ice-cold methanol and then incubated with Anti-AVPR1A Recombinant Rabbit Superclonal™ Antibody (Product # 711640 at a concentration of 1 µg/mL). Cells were then incubated with Alexa488-conjugated seco... View More
产品信息
711640
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
克隆号
7HCLC
抗原
Peptide corresponding to human AVPR1A [aa398-aa418]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2723955
产品详细信息
This antibody is predicted to react with Monkey, Rabbit, Cat.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.
靶标信息
Vasopressin receptor 1a (AVPR1A) is a receptor for arginine vasopressin. The activity of this receptor is mediated by G-proteins which activate a phosphatidyl-inositol-calcium second messenger system. AVPR1A has been involved in social behaviors, including affiliation and attachment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Antidiuretic hormone receptor 1a; AVPR V1a; SCCL vasopressin subtype 1a receptor; V1-vascular vasopressin receptor AVPR1A; V1a receptor; V1a vasopressin receptor; V1aR; Vascular/hepatic-type arginine vasopressin receptor; Vasopressin V1a receptor; Vasopressin V1aR
基因别名: AVPR V1a; AVPR1; AVPR1A; V1aR
UniProt ID: (Human) P37288
Entrez Gene ID: (Human) 552
regulation of systemic arterial blood pressure by vasopressin
maternal aggressive behavior
positive regulation of systemic arterial blood pressure
generation of precursor metabolites and energy
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
positive regulation of cytosolic calcium ion concentration
negative regulation of female receptivity
grooming behavior
blood circulation
positive regulation of cell proliferation
positive regulation of heart rate
positive regulation of glutamate secretion
myotube differentiation
calcium-mediated signaling
telencephalon development
positive regulation of cell growth
positive regulation of prostaglandin biosynthetic process
positive regulation of cellular pH reduction
cellular response to hormone stimulus
social behavior
positive regulation of renal sodium excretion
cellular response to water deprivation
maternal behavior
sperm ejaculation
penile erection
positive regulation of vasoconstriction
response to corticosterone
negative regulation of transmission of nerve impulse
response to peptide
