Invitrogen

Abl2 Polyclonal Antibody

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Abl2 Antibody (PA5-27926) in WB

Western Blot using Abl2 Polyclonal Antibody (Product # PA5-27926). Sample (30 µg of whole cell lysate). Lane A: IMR32. 5% SDS PAGE. Abl2 Polyclonal Antibody (Product # PA5-27926) diluted at 1:1,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

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产品信息

PA5-27926

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 55 and 470 of Human ABL2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.77 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2545402

产品详细信息

Recommended positive controls: IMR32.

Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (97%), Xenopus laevis (96%), Bovine (99%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization. Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. Abl2 is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; c-abl oncogene 2, non-receptor tyrosine kinase; FLJ22224; FLJ31718; FLJ41441; Tyrosine-protein kinase ABL2; Tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene homolog 2

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基因别名: ABL2; ABLL; ARG

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UniProt ID: (Human) P42684

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Entrez Gene ID: (Human) 27

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功能