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Antibody detects endogenous levels of total Acrosin.
ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Acrosin; acrosin light and heavy chain prepropeptide; preproacrosin; proacrosin
基因别名: ACR; ACRS
UniProt ID: (Human) P10323
Entrez Gene ID: (Human) 49