Invitrogen

Actin Polyclonal Antibody

Actin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Actin Antibody (PA5-11571) in IHC (P)

Immunohistochemistry analysis of Actin in formalin-fixed and paraffin-embedded human skeletal muscle tissue. Samples were incubated with Actin polyclonal antibody (Product # PA5-11571) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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产品信息

PA5-11571

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫组化（石蜡） (IHC (P))

1:10-1:50

产品规格

种属反应

Human

已发表种属

Plant

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 189-218 amino acids from the central region of human Actin (ACTB/ACTC)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

纯化类型

Ammonium sulfate precipitation, Size-exclusion - Dialysis

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2223355

产品详细信息

This antibody is predicted to react with bovine, chicken, canine, equine, hamster, mouse, porcine, non-human primate, rat, rabbit and Xenopus, yeast and zebrafish based on sequence homology.

靶标信息

Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton. Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis. In vertebrates there are three groups of actin isoforms: alpha, beta and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exists in most cell types as components of the cytoskeleton and as mediators of internal cell motility.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature.

Developmental cell

Tang Y,Gao CC,Gao Y,Yang Y,Shi B,Yu JL,Lyu C,Sun BF,Wang HL,Xu Y,Yang YG,Chong K

PA5-11571 was used in Western Blotting to investigate how RNA 5-methylcytosine modification specifically regulates heat response in the monocot model plant rice (Oryza sativa).

Mon May 04 00:00:00 UTC 2020

生物信息学

蛋白别名: Actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; Actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; actin, beta; Actin, cytoplasmic 1; Actin, cytoplasmic 1, N-terminally processed; Actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; Actin, gamma-enteric smooth muscle; Actin, gamma-enteric smooth muscle, intermediate form; actin-like protein; Alpha-actin-1; Alpha-actin-2; Alpha-actin-3; Alpha-cardiac actin; alpha-sma; Atcb; beta cytoskeletal actin; Beta-actin; Cell growth-inhibiting gene 46 protein; cytoskeletal gamma-actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; epididymis luminal protein 176; Gamma-2-actin; Gamma-actin; nemaline myopathy type 3; pan actin; PS1TP5-binding protein 1; RP5-1068B5.2; Smooth muscle gamma-actin

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基因别名: AAT6; ACT; ACTA; ACTA1; ACTA2; ACTA3; ACTB; ACTC; ACTC1; ACTE; ACTG; ACTG1; ACTG2; ACTL3; ACTSA; ACTSG; ACTVS; ASD5; ASMA; BRWS1; BRWS2; CFTD; CFTD1; CFTDM; CMD1R; CMH11; DFNA20; DFNA26; GIG46; HEL-176; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; PS1TP5BP1; SHPM; VSCM