Invitrogen

Actin Muscle Monoclonal Antibody (HHF35)

Actin Muscle Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Actin Muscle Antibody (MA1-10046) in IHC (P)

Immunohistochemistry staining of human smooth muscle (paraffin-embedded sections) with anti-muscle-specific actin (HHF35) Monoclonal antibody (Product # MA1-10046).

Actin Muscle Antibody in Western Blot (WB)

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产品信息

MA1-10046

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

免疫组化 (IHC)

查看9篇已发表文章 9篇已发表文章

免疫组化（石蜡） (IHC (P))

Assay-dependent

免疫组化（冰冻） (IHC (F))

Assay-dependent

免疫细胞化学 (ICC/IF)

Assay-dependent

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产品规格

种属反应

Dog, Chicken, Cat, Human, Mouse, Non-human primate, Rabbit, Rat

已发表种属

Human, Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

HHF35

抗原

SDS extracted protein fraction of human myocardium

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

15mM sodium azide

保存条件

4° C, do not freeze

运输条件

Ambient (domestic); Wet ice (international)

AB_11154239

产品详细信息

This antibody recognizes muscle-specific alpha and gamma actin (42 kDa) in various species. This antibody stains skeletal, smooth and myocardial cells as well as myoepithelial cells and pericytes of small vessels. It is a widely used marker of muscle and muscle-derived cells.

Western Blot: Reducing conditions; Immunohistochemistry (Paraffin): Antigen retrieval steps generally not required, but e.g. in case of arterial smooth muscle cells or myoepithelial cells, pepsin or trypsin pretreatment is recommended.

靶标信息

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess.

International journal of surgical pathology

Lee PW,Yau DT,Lau PP,Chan JK

MA1-10046 was used in immunohistochemistry to report on a case of plexiform fibromyxoma of the stomach

Thu May 01 00:00:00 UTC 2014

Expression of E-cadherin in angiomyolipoma.

Human pathology

Wang Z,Gong Q,Fan Q

MA1-10046 was used in immunohistochemistry to perform a systematic study of E-cadherin expression in angiomyolipoma

Sat Dec 01 00:00:00 UTC 2012

Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.

Diagnostic pathology

Yin WH,Li J,Chan JK

MA1-10046 was used in immunohistochemistry to report on a case of sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression

Thu Apr 12 00:00:00 UTC 2012

Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?

International journal of surgical pathology

Eloy C,Vinagre J,Cameselle-Teijeiro J,Paiva ME,Soares P,Sobrinho-Simões M

MA1-10046 was used in immunohistochemistry to report on a case of tumor-in-tumor of the thyroid with basaloid differentiation

Fri Apr 01 00:00:00 UTC 2011

G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs.

Cell stem cell

Shimoji K,Yuasa S,Onizuka T,Hattori F,Tanaka T,Hara M,Ohno Y,Chen H,Egasgira T,Seki T,Yae K,Koshimizu U,Ogawa S,Fukuda K

MA1-10046 was used in immunocytochemistry to investigate the expression level of G-CSFR in vivo and the role of G-CSF during cardiomyogenesis in vitro and in vivo

Fri Mar 05 00:00:00 UTC 2010

Chorangiosis: the potential role of smoking and air pollution.

Pathology, research and practice

Akbulut M,Sorkun HC,Bir F,Eralp A,Duzcan E

MA1-10046 was used in immunohistochemistry to investigate the role of smoking and air pollution in the development of chorangiosis

Tue May 19 00:00:00 UTC 2009

Microfabrication-based modulation of embryonic stem cell differentiation.

Lab on a chip

Park J,Cho CH,Parashurama N,Li Y,Berthiaume F,Toner M,Tilles AW,Yarmush ML

MA1-10046 was used in immunocytochemistry to study the effect of microfabricated adhesive stencils on embryonic stem cell differentiation

Wed Aug 01 00:00:00 UTC 2007

Myointimoma of the glans penis.

Pathology international

Vardar E,Gunlusoy B,Arslan M,Kececi S

MA1-10046 was used in immunohistochemistry to report on a case of myointimoma of the glans penis

Thu Mar 01 00:00:00 UTC 2007

Ectopic cervical anaplastic ependymoma.

Pathology international

Wang Z,Huang G,Yan P,Liang R,Wang J,Yan Q,Zhang J,Cheng H,Hu P,Ma MJ

MA1-10046 was used in immunohistochemistry to report on a case of ectopic cervical anaplastic ependymoma

Thu Dec 01 00:00:00 UTC 2005

Cutaneous lymphoid hyperplasia and other lymphoid infiltrates of the breast nipple: a retrospective clinicopathologic study of fifty-six patients.

The American Journal of dermatopathology

Boudova L,Kazakov DV,Sima R,Vanecek T,Torlakovic E,Lamovec J,Kutzner H,Szepe P,Plank L,Bouda J,Hes O,Mukensnabl P,Michal M

MA1-10046 was used in immunohistochemistry to study the clinicopathological spectrum of lymphoproliferations and other lymphoid infiltration of the breast nipple

Sat Oct 01 00:00:00 UTC 2005

Epstein-Barr virus-associated smooth muscle tumour: a distinctive mesenchymal tumour of immunocompromised individuals.

Pathology

Cheuk W,Li PC,Chan JK

MA1-10046 was used in immunohistochemistry to report on a case of Epstein-Barr virus-associated smooth muscle tumour

Sat Jun 01 00:00:00 UTC 2002

生物信息学

蛋白别名: a-actin; actin alpha 1; actin alpha cardiac; actin alpha cardiac 1; actin, alpha 1, skeletal muscle; Actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; Actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; Actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; Actin, cytoplasmic type 5; actin, cytoplasmic, type 5; actin, gamma 1; actin, gamma 1 propeptide; actin, gamma 2, smooth muscle, enteric; actin, gamma, cytoplasmic 1; Actin, gamma-enteric smooth muscle; Actin, gamma-enteric smooth muscle, intermediate form; actin-like protein; Alpha-actin; alpha-actin cardiac; Alpha-actin-1; Alpha-actin-2; Alpha-actin-3; Alpha-cardiac actin; alpha-sma; alpha-smooth muscle actin; alphac-actin; beta-actin FE-3; cardiac actin; Cell growth-inhibiting gene 46 protein; cytoplasmic 2; cytoplasmic beta-actin; cytoplasmic type 5; cytoskeletal gamma-actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; epididymis luminal protein 176; gamma 1 propeptide; Gamma-2-actin; Gamma-actin; gamma-enteric smooth muscle actin; nemaline myopathy type 3; RP5-1068B5.2; smooth muscle alpha-actin; Smooth muscle gamma-actin; type 5

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基因别名: 0610041G09Rik; a-SMA; AA959943; AAT6; ACT; Act-4; Act4; ACTA; Acta-2; ACTA1; ACTA2; ACTA3; ACTC; Actc-1; ACTC1; ACTE; ACTG; ACTG1; ACTG2; ACTGE; actin; Actl; ACTL3; Acts; ACTSA; ACTSG; Actsk-1; ACTVS; AL023024; alphaSMA; ASD5; ASMA; BRWS2; CFTD; CFTD1; CFTDM; CMD1R; CMH11; cytoplasmic; DFNA20; DFNA26; E51; GAMMA-ACTIN; GIG46; HEL-176; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; RCJMB04_1h13; SHPM; SMalphaA; SMGA; VSCM

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