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Alomone Labs, LTD
Adenylate Cyclase 3 (AC3) (extracellular) Polyclonal Antibody, Atto™ 488
FIGURE: 1 / 1
Adenylate Cyclase 3 (AC3) (extracellular) Antibody (AAR-043-AG-50UL) in ICC/IF
Expression of Adenylate cyclase type IIIin rat U-87 MG cells - Cell surface detection of Adenylate cyclase type III in intact living rat U-87 MG cells. A. Extracellular staining of cells using Anti-Adenylate Cyclase 3 (AC3) (extracellular)-ATTO Fluor-488 Antibody (#AAR-043-AG), (1:25), (green). B. Merge of A with live view of the cells.
Product Details
AAR-043-AG-50UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)KHVADEMLKDMKKDE, corresponding to amino acid residues 285-299 of rat ADCY3, 3rd extracellular loop
Conjugate
Excitation/Emission Max
501/523 nm
Form
Lyophilized
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AC-III; AC3; Adenylate cyclase type 3; Adenylate cyclase type III; Adenylate cyclase, olfactive type; Adenylyl cyclase 3; adenylyl cyclase, type III; ATP pyrophosphate-lyase 3; type III adenylyl cyclase
Gene Aliases: AC-III; AC3; ADCY3; KIAA0511; mKIAA0511
UniProt ID: (Human) O60266, (Rat) P21932, (Mouse) Q8VHH7
Entrez Gene ID: (Human) 109, (Rat) 64508, (Mouse) 104111
cAMP biosynthetic process
female meiotic division
sensory perception of smell
cyclic nucleotide biosynthetic process
intracellular signal transduction
renal water homeostasis
signal transduction
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
single fertilization
acrosome reaction
olfactory learning
cAMP-mediated signaling
sperm motility
activation of protein kinase A activity
cellular response to glucagon stimulus
cellular response to forskolin
response to stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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