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Adenylate Kinase 1 Antibody (PA5-28354) in IHC (P)
Adenylate Kinase 1 Polyclonal Antibody detects Adenylate kinase 1 protein at cytosol on Ca922 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Ca922 xenograft. Adenylate Kinase 1 Polyclonal Antibody (Product # PA5-28354) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-28354
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 188 of Human Adenylate kinase 1
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545830
产品详细信息
Recommended positive controls: A549, HCT116, mouse brown adipose tissue.
Predicted reactivity: Mouse (89%), Rat (90%), Xenopus laevis (80%), Dog (97%), Chicken (86%), Sheep (96%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adenylate kinase isoenzyme 1; Adenylate monophosphate kinase; AK 1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; cytosolic adenylate kinase; Myokinase; testis secretory sperm binding protein Li 58j
基因别名: Ak-1; AK1; B430205N08Rik; HTL-S-58j
UniProt ID: (Human) P00568, (Mouse) Q9R0Y5
Entrez Gene ID: (Human) 203, (Mouse) 11636
nucleoside diphosphate phosphorylation
ADP biosynthetic process
cell cycle arrest
nucleoside triphosphate biosynthetic process
nucleobase-containing small molecule interconversion
AMP metabolic process
ATP metabolic process
nucleobase-containing compound metabolic process
positive regulation of glucose transport
phosphorylation
inosine biosynthetic process
nucleotide phosphorylation
