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Adenylate Kinase 2 Antibody (PA5-28611) in ICC/IF
Adenylate Kinase 2 Polyclonal Antibody detects Adenylate kinase 2 protein at mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in 2% paraformaldehyde/culture medium at 37°C for 30 min. Green: Adenylate kinase 2 protein stained by Adenylate Kinase 2 Polyclonal Antibody (Product # PA5-28611) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-28611
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 239 of Human Adenylate kinase 2
偶联物
形式
Liquid
浓度
0.35 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546087
产品详细信息
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain.
Predicted reactivity: Mouse (95%), Rat (94%), Zebrafish (81%), Xenopus laevis (82%), Rhesus Monkey (100%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adenylate kinase 2, mitochondrial; adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}; adenylate kinase isoenzyme 2, mitochondrial; Adenylate monophosphate kinase; adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}; AK 2; AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}; ATP-AMP transphosphorylase 2; ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}; ATP:AMP phosphotransferase; ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}; testis secretory sperm-binding protein Li 220n
基因别名: ADK2; Ak-2; AK2; D4Ertd220e
UniProt ID: (Human) P54819, (Rat) P29410, (Mouse) Q9WTP6
Entrez Gene ID: (Human) 204, (Rat) 24184, (Mouse) 11637
liver development
oxidative phosphorylation
ADP biosynthetic process
brain development
nucleobase-containing small molecule interconversion
AMP metabolic process
dATP metabolic process
nucleotide phosphorylation
response to thyroid hormone
ATP metabolic process
adenine metabolic process
nucleobase-containing compound metabolic process
phosphorylation
