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AdoHcyase 2 Antibody (MA5-49301) in WB
Western blot analysis of IRBIT/AHCYL1 using IRBIT/AHCYL1 antibody (Product # MA5-49301). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human Hela whole cell lysates; Lane 2: human 293T whole cell lysates; Lane 3: human MCF-7 whole cell lysates; Lane 4: rat brain tissue lysates; Lane 5: rat pancreas tissue lysates; Lane 6: mouse brain tissue lysates; Lane 7: mouse pancreas tissue ... View More
Product Details
MA5-49301
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2E7D9
Immunogen
E.coli-derived human IRBIT/AHCYL1 recombinant protein (Position: E14-K57).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_3074959
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human 293T whole cell, human MCF-7 whole cell, rat brain tissue, rat pancreas tissue, mouse brain tissue, mouse pancreas tissue. Flow: K562 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adenosylhomocysteinase-like 1; AdoHcyase 2; DC-expressed AHCY-like molecule; dendritic cell expressed AHCY-like protein; inositol 1,4,5-trisphosphate receptor-binding protein; IP(3)Rs binding protein released with IP(3); IP3R binding protein released with inositol 1,4,5-trisphosphate; IP3R-binding protein released with inositol 1,4,5-trisphosphate; IRBIT; protein phosphatase 1, regulatory subunit 78; Putative adenosylhomocysteinase 2; s adenosylhomocysteine hydrolase; S-adenosyl homocysteine hydrolase homolog; S-adenosyl-L-homocysteine hydrolase 2; S-adenosylhomocysteine hydrolase, related sequence 3; S-adenosylhomocysteine hydrolase-like 1; S-adenosylhomocysteine hydrolase-like protein 1
Gene Aliases: 1110034F20Rik; AA409031; AA414901; Ahcy-rs3; AHCYL1; DCAL; IRBIT; PPP1R78; PRO0233; XPVKONA
UniProt ID: (Human) O43865, (Rat) B5DFN2, (Mouse) Q80SW1
Entrez Gene ID: (Human) 10768, (Rat) 362013, (Mouse) 229709
mRNA polyadenylation
protein export from nucleus
one-carbon metabolic process
positive regulation of sodium ion transport
regulation of mRNA 3'-end processing
regulation of ion transmembrane transporter activity
S-adenosylmethionine cycle
regulation of anion transport
biological_process
angiotensin-activated signaling pathway
epithelial fluid transport
response to calcium ion
regulation of cardiac conduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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