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Aldh1l1 Antibody (600-101-HB6) in ICC/IF
Immunofluorescence Microscopy of Goat anti-Aldh1l1 antibody. Cells: HepG2 cells. Fixation: 100% MeOH. Permeabilization: 0.3%Triton X-100. Primary antibody: Anti-Aldh1l1 antibody at 15µg/mL overnight at 2-8°C. Secondary antibody: Donkey Anti-Goat IgG DyLight™ 488 Conjugated Preadsorbed (p/n 605-741-125) at 5µg/mL for 1 h at RT. Localization: cytoplasm. Images were deconvoluted. Staining: (A) DAPI. (B) Anti-Adlh1l1 antibody+secondary. (C) Merged A+B. (D) Secondary Only.
产品信息
600-101-HB6
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-Aldh1l1 antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of mouse Aldh1l1 conjugated to Keyhole Limpet Hemocyanin (KLH).
偶联物
形式
Liquid
浓度
1.03 mg/mL
纯化类型
Affinity chromatography
保存液
0.02M potassium phosphate, pH 7.2, with 0.5M NaCl
内含物
0.01% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This affinity purified antibody is directed against mouse Aldh1l1. A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to human and rat.
靶标信息
ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; 10fTHF; 10FTHFDH; Aldehyde dehydrogenase family 1 member L1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; formyltetrahydrofolate dehydrogenase
基因别名: 1810048F20Rik; Aldh1l1; FDH; Fthfd; Neut2
UniProt ID: (Mouse) Q8R0Y6
Entrez Gene ID: (Mouse) 107747
catalytic activity
aldehyde dehydrogenase (NAD) activity
aldehyde dehydrogenase [NAD(P)+] activity
protein binding
methyltransferase activity
formyltetrahydrofolate dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
hydroxymethyl-, formyl- and related transferase activity
protein complex binding
aldehyde dehydrogenase (NADP+) activity
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
