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Alsin Antibody (PA5-13426) in IHC (P)
Immunohistochemistry analysis of Alsin in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with Alsin polyclonal antibody (Product # PA5-13426) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-13426
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Size-exclusion - Dialysis, Ammonium sulfate precipitation
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2226186
Product Specific Information
This antibody is predicted to react with rat based on sequence homology.
Target Information
The function of this protein remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alsin; amyotrophic lateral sclerosis 2 (juvenile); amyotrophic lateral sclerosis 2 (juvenile) homolog; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Amyotrophic lateral sclerosis 2 protein; Amyotrophic lateral sclerosis 2 protein homolog; amyotrophic lateral sclerosis protein 2 homolog; FLJ31851; MGC87187
Gene Aliases: 3222402C23Rik; 9430073A21Rik; ALS2; ALS2CR6; Alsin; ALSJ; IAHSP; KIAA1563; mKIAA1563; PLSJ
UniProt ID: (Human) Q9HCK9, (Mouse) Q920R0
Entrez Gene ID: (Human) 57679, (Mouse) 74018
guanyl-nucleotide exchange factor activity
Ran guanyl-nucleotide exchange factor activity
protein binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
Rac guanyl-nucleotide exchange factor activity
protein homodimerization activity
protein serine/threonine kinase activator activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
identical protein binding
Rac GTPase binding
behavioral fear response
receptor recycling
response to oxidative stress
endosome organization
lysosomal transport
axonogenesis
neuromuscular junction development
locomotory behavior
protein localization
cell death
vesicle organization
endosomal transport
Rac protein signal transduction
regulation of Rho protein signal transduction
synaptic transmission, glutamatergic
regulation of GTPase activity
positive regulation of GTPase activity
positive regulation of protein kinase activity
neuron projection morphogenesis
protein homooligomerization
positive regulation of protein serine/threonine kinase activity
in utero embryonic development
positive regulation of Rac protein signal transduction
regulation of endosome size
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