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Alsin Antibody (PA5-13426) in IHC (P)
Immunohistochemistry analysis of Alsin in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with Alsin polyclonal antibody (Product # PA5-13426) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-13426
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Size-exclusion - Dialysis, Ammonium sulfate precipitation
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2226186
产品详细信息
This antibody is predicted to react with rat based on sequence homology.
靶标信息
The function of this protein remains unknown.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alsin; amyotrophic lateral sclerosis 2 (juvenile); amyotrophic lateral sclerosis 2 (juvenile) homolog; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Amyotrophic lateral sclerosis 2 protein; Amyotrophic lateral sclerosis 2 protein homolog; amyotrophic lateral sclerosis protein 2 homolog; FLJ31851; MGC87187
基因别名: 3222402C23Rik; 9430073A21Rik; ALS2; ALS2CR6; Alsin; ALSJ; IAHSP; KIAA1563; mKIAA1563; PLSJ
UniProt ID: (Human) Q9HCK9, (Mouse) Q920R0
Entrez Gene ID: (Human) 57679, (Mouse) 74018
guanyl-nucleotide exchange factor activity
Ran guanyl-nucleotide exchange factor activity
protein binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
Rac guanyl-nucleotide exchange factor activity
protein homodimerization activity
protein serine/threonine kinase activator activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
identical protein binding
Rac GTPase binding
behavioral fear response
receptor recycling
response to oxidative stress
endosome organization
lysosomal transport
axonogenesis
neuromuscular junction development
locomotory behavior
protein localization
cell death
vesicle organization
endosomal transport
Rac protein signal transduction
regulation of Rho protein signal transduction
synaptic transmission, glutamatergic
regulation of GTPase activity
positive regulation of GTPase activity
positive regulation of protein kinase activity
neuron projection morphogenesis
protein homooligomerization
positive regulation of protein serine/threonine kinase activity
in utero embryonic development
positive regulation of Rac protein signal transduction
regulation of endosome size
