Invitrogen

Angiopoietin 2 Recombinant Rabbit Monoclonal Antibody (ARC0571)

Angiopoietin 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 3

Angiopoietin 2 Antibody (MA5-35095) in IHC (P)

Immunohistochemistry analysis of Angiopoietin 2 in paraffin-embedded human esophageal. Samples were incubated with Angiopoietin 2 Monoclonal antibody (Product # MA5-35095) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Angiopoietin 2 Antibody in Western Blot (WB)

Product Image Gallery

产品信息

MA5-35095

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:6,000

免疫组化（石蜡） (IHC (P))

1:100-1:2,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

ARC0571

抗原

A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ANGPT2 (O15123)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.4 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2849000

产品详细信息

Immunogen sequence: LTFPNSTEEI KAYCDMEAGG GGWTIIQRRE DGSVDFQRTW KEYKVGFGNP SGEYWLGNEF VSQLTNQQRY VLKIHLKDWE GNEAYSLYEH FYLSSEELNY R

靶标信息

ANG-2 binds to the endothelial cell specific receptor Tie-2, but, in contrast to ANG-1, does not induce tyrosine phosphorylation. Consequently, ANG-2 modulates ANG-1 activation of Tie-2 and, depending on the physiological and biochemical environment, can act either as an agonist or antagonist of Tie-2 induced angiogenesis. The signaling interactions of ANG-1, ANG-2 and Tie-2, along with less characterized ANG-3 and ANG-4, are required for embryonic and adult angiogenesis. Physiologically, ANG-1 and ANG-2 are associated with sprouting, tube formation, and structural integrity of newly formed blood vessels. Mature human ANG-2 is a secreted protein containing 480 amino acid residues. ANG-2 is composed of an alpha-helix-rich coiled coil N-terminal domain and fibrinogen-like C-terminal domain. ANG-2 exists predominantly in the form of a disulfide-linked dimer.

仅用于科研。不用于诊断过程。未经明确授权不得转售。