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Angiotensin-(1-7) Mas Receptor Antibody (AAR-013-200UL) in IHC (P)
Expression of Angiotensin- (1-7) Mas Receptor in rat kidney - Immunohistochemical staining of rat kidney paraffin embedded sections using Anti-Angiotensin- (1-7) Mas Receptor Antibody (#AAR-013), (1:100). Angiotensin- (1-7) Mas receptor (brown staining)isdetected in proximal tubules (PT) and distal tubules (DT) in the renal cortex. Collecting ducts (CD) are less stained and both glomeruli (G) and blood vess... View More
产品信息
AAR-013-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KIRKNTWASHSSK, corresponding to amino acid residues 212-224 of the rat Angiotensin-(1-7) Mas receptor, 3rd intracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a 7-transmembrane segment following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: angiotensin-(1-7) receptor; MAS proto-oncogene; Mas-related G protein-coupled receptor A; MAS1 oncogene; Mas1 proto-oncogene; MGC119966; Proto-oncogene Mas
基因别名: c-mas; MAS; Mas-1; MAS1; MGRA
UniProt ID: (Human) P04201, (Rat) P12526, (Mouse) P30554
Entrez Gene ID: (Human) 4142, (Rat) 25153, (Mouse) 17171
negative regulation of protein phosphorylation
G-protein coupled receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
spermatogenesis
cell proliferation
positive regulation of cell proliferation
male gonad development
anatomical structure morphogenesis
response to activity
hippocampus development
response to gonadotropin
angiotensin-activated signaling pathway
response to drug
positive regulation of DNA replication
regulation of inflammatory response
positive regulation of inositol phosphate biosynthetic process
protein kinase C signaling
response to peptide hormone
cellular response to peptide hormone stimulus
signal transduction
