NeoBiotechnologies

Annexin A1 Monoclonal Antibody (ANXA1, 1671)

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抗体检测数据 (5)

Annexin A1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Annexin A1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Annexin A1 Antibody (301-MSM1-P1ABX) in IHC (P)

Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human prostate tissue using Annexin A1 Monoclonal Antibody (Product # 301-MSM1-P1ABX).

Annexin A1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Annexin A1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Annexin A1 Antibody in Western Blot (WB)

Annexin A1 Antibody in Flow Cytometry (Flow)

Annexin A1 Antibody in SDS-PAGE (SDS-PAGE)

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Annexin A1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human prostate tissue using Annexin A1 Monoclonal Antibody (Product # 301-MSM1-P1ABX).

Annexin A1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human spleen tissue using Annexin A1 Monoclonal Antibody (Product # 301-MSM1-P1ABX).

Annexin A1 Antibody in Western Blot (WB) — Western Blot analysis of A549 cell lysate using Annexin A1 Monoclonal Antibody (Product # 301-MSM1-P1ABX).

Annexin A1 Antibody in Flow Cytometry (Flow) — Flow Cytometry analysis of PFA-fixed HeLa cells using Annexin A1 Monoclonal Antibody (Product # 301-MSM1-P1ABX) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).

Annexin A1 Antibody in SDS-PAGE (SDS-PAGE) — SDS-PAGE Analyis Purified Annexin A1 Monoclonal Antibody (Product # 301-MSM1-P1ABX). Confirmation of Purity and Integrity of Antibody.

产品信息

301-MSM1-P1ABX

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

-

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

-

免疫细胞化学 (ICC/IF)

2-4 µg/mL

-

流式细胞分析 (Flow)

1-2 µg/10^6 cells

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b, kappa

分类

Monoclonal

类型

Antibody

克隆号

ANXA1, 1671

抗原

Recombinant full length human Annexin A1 protein

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C or -80°C if preferred

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

靶标信息

Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ANAX1; Annexin A1; Annexin I; annexin I (lipocortin I); Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; p35; Phospholipase A2 inhibitory protein; RP11-71A24.1

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基因别名: ANX1; ANXA1; LPC1

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UniProt ID: (Human) P04083

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Entrez Gene ID: (Human) 301

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single-stranded DNA binding single-stranded RNA binding helicase activity receptor binding structural molecule activity calcium ion binding protein binding phospholipid binding calcium-dependent phospholipid binding phospholipase A2 inhibitor activity protein binding, bridging double-stranded DNA-dependent ATPase activity annealing helicase activity protein homodimerization activity calcium-dependent protein binding cadherin binding involved in cell-cell adhesion calcium-binding protein

DNA strand renaturation neutrophil homeostasis adaptive immune response monocyte chemotaxis regulation of leukocyte migration phagocytosis inflammatory response signal transduction cell surface receptor signaling pathway G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of cell shape response to X-ray myoblast migration involved in skeletal muscle regeneration peptide cross-linking insulin secretion keratinocyte differentiation prostate gland development endocrine pancreas development positive regulation of vesicle fusion positive regulation of prostaglandin biosynthetic process actin cytoskeleton reorganization response to estradiol DNA duplex unwinding regulation of interleukin-1 production positive regulation of interleukin-2 production positive regulation of neutrophil apoptotic process DNA rewinding gliogenesis positive regulation of T cell proliferation response to drug negative regulation of apoptotic process response to peptide hormone estrous cycle innate immune response positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of exocytosis alpha-beta T cell differentiation regulation of hormone secretion arachidonic acid secretion regulation of inflammatory response cellular response to hydrogen peroxide hepatocyte differentiation prolactin secretion response to interleukin-1 cellular response to glucocorticoid stimulus granulocyte chemotaxis positive regulation of wound healing neutrophil clearance positive regulation of G1/S transition of mitotic cell cycle negative regulation of phospholipase A2 activity negative regulation of interleukin-8 secretion