Invitrogen

Annexin A4 Recombinant Rabbit Monoclonal Antibody (JG37-83)

Annexin A4 Antibody in Immunocytochemistry (ICC/IF)

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Annexin A4 Antibody (MA5-34769) in ICC/IF

Immunofluorescent analysis of Annexin IV in HepG2 cells (green). Samples were fixed in paraformaldehyde and permeabilised with 0.25% Triton X100/PBS, incubated with Annexin IV monoclonal antibody (Product # MA5-34769), followed by DAPI (blue).

Annexin A4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Annexin A4 Antibody in Western Blot (WB)

Annexin A4 Antibody in Flow Cytometry (Flow)

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产品信息

MA5-34769

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

流式细胞分析 (Flow)

1:50-1:100

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

JG37-83

抗原

Recombinant protein within Human Human Annexin IV aa 10-107

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles, store in dark

运输条件

Wet ice

AB_2848677

产品详细信息

Positive Control: Human liver tissue lysate, A549, HepG2, SiHa, human colon cancer tissue, human kidney tissue.

靶标信息

Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 35-beta calcimedin; Annexin A4; Annexin IV; annexin IV (placental anticoagulant protein II); Annexin-4; ANXA 4; Carbohydrate-binding protein p33/p41; Chromobindin-4; Endonexin I; epididymis secretory protein Li 274; Lipocortin IV; P32.5; PAP-II; Placental anticoagulant protein II; PP4-X; proliferation-inducing gene 28; proliferation-inducing protein 28; Protein II

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基因别名: ANX4; ANXA4; HEL-S-274; P32.5; PAP-II; PIG28; PP4-X; ZAP36

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UniProt ID: (Human) P09525

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Entrez Gene ID: (Human) 307

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功能

phospholipase inhibitor activity calcium ion binding protein binding calcium-dependent phospholipid binding identical protein binding calcium-dependent protein binding NF-kappaB binding calcium-binding protein

参与通路

regulation of transcription from RNA polymerase II promoter signal transduction Notch signaling pathway epithelial cell differentiation negative regulation of NF-kappaB transcription factor activity negative regulation of apoptotic process negative regulation of catalytic activity negative regulation of interleukin-8 secretion