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Anoctamin-6 (extracellular) Antibody (ACL-016-200UL) in WB
Western blot analysis of human THP-1 monocytic leukemia cell line lysate (lanes 1 and 3) and human MEG-01 megakaryoblastic leukemia cell line lysate (lanes 2 and 4): - 1,2. Anti-Anoctamin-6 (extracellular) Antibody (#ACL-016), (1:200).3,4. Anti-Anoctamin-6 (extracellular) Antibody , preincubated with Anoctamin-6 (extracellular) Blocking Peptide (#BLP-CL016).
产品信息
ACL-016-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KLPKNINGTDPIQK, corresponding to amino acid residues 487-500 of human ANO6, 2nd extracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
May act as a calcium-activated chloride channel.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Anoctamin-6; SCAN channel; Small-conductance calcium-activated nonselective cation channel; Transmembrane protein 16F
基因别名: 2900059G15Rik; AA407480; ANO6; AW554778; BDPLT7; F730003B03Rik; SCTS; TMEM16F
UniProt ID: (Human) Q4KMQ2, (Mouse) Q6P9J9
Entrez Gene ID: (Human) 196527, (Rat) 315272, (Mouse) 105722
calcium activated cation channel activity
intracellular calcium activated chloride channel activity
voltage-gated ion channel activity
voltage-gated chloride channel activity
protein binding
phospholipid scramblase activity
protein homodimerization activity
molecular_function
chloride channel activity
dendritic cell chemotaxis
activation of blood coagulation via clotting cascade
cation transport
chloride transport
blood coagulation
phospholipid transport
phospholipid scrambling
bone mineralization involved in bone maturation
regulation of anion transport
calcium activated phospholipid scrambling
calcium activated phosphatidylserine scrambling
calcium activated phosphatidylcholine scrambling
calcium activated galactosylceramide scrambling
phosphatidylserine exposure on apoptotic cell surface
phosphatidylserine exposure on blood platelet
cation transmembrane transport
positive regulation of potassium ion export
chloride transmembrane transport
positive regulation of endothelial cell apoptotic process
lipid transport
positive regulation of bone mineralization
bleb assembly
ion transmembrane transport
positive regulation of ion transmembrane transport
purinergic nucleotide receptor signaling pathway
sodium ion transmembrane transport
positive regulation of apoptotic process
negative regulation of cell volume
pore complex assembly
positive regulation of phagocytosis, engulfment
calcium ion transmembrane transport
positive regulation of monocyte chemotaxis
regulation of anion transmembrane transport
transport
ion transport
regulation of ion transmembrane transport
