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产品信息
MA5-15265
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2G1H11, 1F1E8
抗原
Purified recombinant fragment of human Apoa5 expressed in E. Coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10979343
产品详细信息
MA5-15265 targets APOA5 in indirect ELISA, IF and WB applications and shows reactivity with Human samples.
The MA5-15265 immunogen is purified recombinant fragment of human Apoa5 expressed in E. Coli.
.
靶标信息
Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but several evidences from vitro studies indicate that this apolipoprotein involves in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Apo-AV; Apolipoprotein A-V; apolipoprotein A-V precursor variant 3; Apolipoprotein A5; apolipoprotein AV; FLJ97995; MGC126836; MGC126838; Regeneration-associated protein 3
基因别名: APOA5; APOAV; RAP3; UNQ411/PRO773
UniProt ID: (Human) Q6Q788
Entrez Gene ID: (Human) 116519
phospholipid binding
enzyme activator activity
heparin binding
lipid binding
cholesterol binding
cholesterol transporter activity
enzyme binding
phosphatidylcholine binding
lipase binding
low-density lipoprotein particle receptor binding
phosphatidylcholine-sterol O-acyltransferase activator activity
lipase activator activity
lipoprotein lipase activator activity
lipoprotein particle receptor binding
apolipoprotein
triglyceride metabolic process
cholesterol biosynthetic process
lipid transport
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
triglyceride catabolic process
regulation of intestinal cholesterol absorption
neuron projection regeneration
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
high-density lipoprotein particle assembly
lipoprotein metabolic process
tissue regeneration
cholesterol homeostasis
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
phosphatidylcholine metabolic process
positive regulation of receptor-mediated endocytosis
positive regulation of lipid catabolic process
positive regulation of lipoprotein lipase activity
acylglycerol homeostasis
triglyceride homeostasis
