NeoBiotechnologies

Apolipoprotein D/APO-D Monoclonal Antibody (APOD/3413)

Apolipoprotein D/APO-D Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Apolipoprotein D/APO-D Antibody (347-MSM3-P1) in IHC (P)

Formalin-fixed, paraffin-embedded human liver stained with Apolipoprotein D Mouse Monoclonal Antibody (APOD/3413).

Apolipoprotein D/APO-D Antibody in Peptide array (ARRAY)

Apolipoprotein D/APO-D Antibody in Immunoelectrophoresis (IE)

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产品信息

347-MSM3-P1

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

肽阵列 (Array)

Assay-dependent

免疫电泳 (IE)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2c, kappa

分类

Monoclonal

类型

Antibody

克隆号

APOD/3413

抗原

Human recombinant APOD protein fragment (around aa21-119).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4° C

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Antibody is stable for 24 months.

Positive Control: Human liver, kidney or spleen. Cellular Localization: Secreted.

Specificity Comments: Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.

靶标信息

Apolipoprotein D (APOD) is a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.

仅用于科研。不用于诊断过程。未经明确授权不得转售。