Invitrogen

Aquaporin 1 Recombinant Rabbit Monoclonal Antibody (JM10-98)

Aquaporin 1 Antibody in Immunocytochemistry (ICC/IF)

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Aquaporin 1 Antibody (MA5-32593) in ICC/IF

Immunofluorescence analysis of AQP1 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Aquaporin 1 Recombinant Rabbit Monoclonal Antibody (JM10-98) (Product # MA5-32593) at 5 µg/mL in 0.1% BSA, incubated a... View More

Aquaporin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Aquaporin 1 Antibody in Western Blot (WB)

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产品信息

MA5-32593

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2000-1:5000

免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:200-1:1000

免疫细胞化学 (ICC/IF)

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

JM10-98

抗原

Synthetic peptide within Human AQP1 aa 245-269

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2809870

产品详细信息

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate.

Nature communications

Parichha A,Suresh V,Chatterjee M,Kshirsagar A,Ben-Reuven L,Olender T,Taketo MM,Radosevic V,Bobic-Rasonja M,Trnski S,Holtzman MJ,Jovanov-Milosevic N,Reiner O,Tole S

MA5-32593 was used in Immunohistochemistry to study the presence of molecules downstream of cannonical Wnt signaling in vivo at embryonic stages in the human and mouse choroid plexus.

Wed Feb 02 00:00:00 UTC 2022

生物信息学

蛋白别名: AQP 1; AQP CHIP; AQP-1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; channel-like integral membrane protein, 28-kDa; CHIP 28; Colton blood group; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; MGC26324; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule

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基因别名: AQP-CHIP; AQP1; CHIP28; CO

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UniProt ID: (Human) P29972, (Mouse) Q02013, (Rat) P29975

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Entrez Gene ID: (Human) 358, (Mouse) 11826, (Rat) 25240

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功能