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Aquaporin 4 (AQP4) (300-314) Polyclonal Antibody

Aquaporin 4 (AQP4) (300-314) Antibody in Immunohistochemistry (Frozen) (IHC (F))

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Aquaporin 4 (AQP4) (300-314) Antibody (AQP-014-GP200UL) in IHC (F)

Expression of Aquaporin 4 in mouse hippocampus. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Guinea Pig Anti-Aquaporin 4 (AQP4) (300-314) Antibody (#AQP-014-GP), (1:200), followed by goat Anti-guinea pig - Alexa Fluor-594. A. Staining in the hippocampal CA1 region, showed immunoreactivity (red) in blood vessel outlines (arrows). B. Pre-incubation of the Antibody with Aqua... View More

Aquaporin 4 (AQP4) (300-314) Antibody in Western Blot (WB)

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产品信息

AQP-014-GP200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:400

免疫组化（冰冻） (IHC (F))

1:300

产品规格

种属反应

Mouse, Rat

宿主/亚型

Guinea pig / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)HVIDIDRGDEKKGKD, corresponding to amino acid residues 300-314 of rat AQP4, Intracellular, C-terminus

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).

靶标信息

In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.

仅用于科研。不用于诊断过程。未经明确授权不得转售。