Invitrogen

Aquaporin 4 Polyclonal Antibody

Aquaporin 4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Aquaporin 4 Antibody (PA5-78812) in IHC (P)

Immunohistochemistry analysis of Aquaporin 4 on paraffin-embedded human glioma tissue. Sample was incubated with Aquaporin 4 polyclonal antibody (Product# PA5-78812).

Aquaporin 4 Antibody in Immunohistochemistry (Frozen) (IHC (F))

Aquaporin 4 Antibody in Western Blot (WB)

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产品信息

PA5-78812

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1-0.5 µg/mL

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

0.5-1 µg/mL

免疫组化（冰冻） (IHC (F))

0.5-1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 4 (295-323aa KPGVVHVIDVDRGEEKKGKDQSGEVLSSV).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

500 µg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 4mg trehalose

内含物

no preservative

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2745928

产品详细信息

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

靶标信息

In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Intranasal Leukemia Inhibitory Factor Attenuates Gliosis and Axonal Injury and Improves Sensorimotor Function After a Mild Pediatric Traumatic Brain Injury.

Neurotrauma reports

D'Mello V,Subramaniam M,Bhalla AP,Saavedra S,Leiba O,Levison SW

PA5-78812 was used in Western Blotting to provide pre-clinical evidence for the use of acute intranasal LIF treatment as a viable therapeutic for pediatric cases of mTBIs.

Wed Apr 26 00:00:00 UTC 2023

Intranasal Leukemia Inhibitory Factor Attenuates Gliosis and Axonal Injury and Improves Sensorimotor Function After a Mild Pediatric Traumatic Brain Injury.

Neurotrauma reports

D'Mello V,Subramaniam M,Bhalla AP,Saavedra S,Leiba O,Levison SW

PA5-78812 was used in Western Blotting to provide pre-clinical evidence for the use of acute intranasal LIF treatment as a viable therapeutic for pediatric cases of mTBIs.