Invitrogen

Aquaporin 5 Recombinant Rabbit Monoclonal Antibody (23GB3225)

Aquaporin 5 Antibody in Immunocytochemistry (ICC/IF)

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Aquaporin 5 Antibody (MA5-52550) in ICC/IF

Immunocytochemistry analysis of Aquaporin 5 in C2C12 cells. Nuclei were stained blue with DAPI; Aquaporin 5 recombinant monoclonal antibody (Product # MA5-52550) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar: 20 μm.

Aquaporin 5 Antibody in Western Blot (WB)

Aquaporin 5 Antibody in Flow Cytometry (Flow)

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产品信息

MA5-52550

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

免疫细胞化学 (ICC/IF)

1:1,000

流式细胞分析 (Flow)

1:2,000

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

23GB3225

抗原

A synthetic peptide of human AQP5 (224-265AA).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

靶标信息

Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.

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