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产品信息
PA5-72771
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ARSB antibody for a 16 amino acid peptide near the carboxy terminus of human ARSB. The immunogen is within amino acids 460 - 510 of ARSB.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2718625
靶标信息
Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Arylsulfatase B; Arylsulfatase B (MPS VI); arylsulfatase B complex; arylsulfatase B regulation; arylsulfatase B structural; arylsulfatase B temporal regulation; ASB; G4S; N-acetylgalactosamine-4-sulfatase
基因别名: 1110007C02Rik; AI480648; ARSB; As-1; As-1r; As-1s; As-1t; As1; As1-r; As1-s; As1-t; ASB; Asr-1; Ast-1; G4S; MPS6
UniProt ID: (Human) P15848, (Rat) P50430, (Mouse) P50429
Entrez Gene ID: (Human) 411, (Rat) 25227, (Mouse) 11881
glycosphingolipid metabolic process
autophagy
lysosome organization
lysosomal transport
central nervous system development
response to nutrient
response to pH
regulation of epithelial cell migration
positive regulation of neuron projection development
chondroitin sulfate catabolic process
response to estrogen
post-translational protein modification
response to methylmercury
colon epithelial cell migration
metabolic process
