Invitrogen

Arylsulfatase G Polyclonal Antibody

Arylsulfatase G Antibody in Immunohistochemistry (IHC)

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Arylsulfatase G Antibody (PA5-54746) in IHC

Immunohistochemical staining of Arylsulfatase G in human colon, liver, lymph node and pancreas using Arylsulfatase G Polyclonal Antibody (Product # PA5-54746) (A) shows similar protein distribution across tissues to an independent Arylsulfatase G Polyclonal Antibody (B).

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产品信息

PA5-54746

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human Arylsulfatase G. Recombinant protein control fragment (Product #RP-93288).

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2638260

产品详细信息

Immunogen sequence: RVPVNVTSTA LLSVLDIFPT VVALAQASLP QGRHFDGVDV SEVLFGRSQP GHRVLFHPNS GAAGEFGALQ TVR

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.

靶标信息

Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.

仅用于科研。不用于诊断过程。未经明确授权不得转售。