Invitrogen

Asporin Polyclonal Antibody

Asporin Antibody in Immunocytochemistry (ICC/IF)

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Asporin Antibody (PA5-13553) in ICC/IF

Immunocytochemistry analysis of Asporin in 293 cells. Samples were incubated in Asporin polyclonal antibody (Product # PA5-13553) followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Asporin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-13553

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫组化（石蜡） (IHC (P))

1:50-1:100

免疫细胞化学 (ICC/IF)

1:10-1:50

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产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 242-269 amino acids from the central region of human ASPN

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.7 mg/mL

纯化类型

Ammonium sulfate precipitation, Size-exclusion - Dialysis

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2060296

靶标信息

ASPN belongs to a family of leucine-rich repeat (LRR) proteins associated with the cartilage matrix. The name asporin reflects the unique aspartate-rich N terminus and the overall similarity to decorin.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement.

Journal of the American Heart Association

Brayson D,Holohan SJ,Bardswell SC,Arno M,Lu H,Jensen HK,Tran PK,Barallobre-Barreiro J,Mayr M,Dos Remedios CG,Tsang VT,Frigiola A,Kentish JC

PA5-13553 was used in Western Blot, Immunocytochemistry to study the major damage at the cellular and tissue levels in the RV of patients with rToF who underwent PVR according to current clinical criteria.

Tue Aug 18 00:00:00 UTC 2020

Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement.

Journal of the American Heart Association

Brayson D,Holohan SJ,Bardswell SC,Arno M,Lu H,Jensen HK,Tran PK,Barallobre-Barreiro J,Mayr M,Dos Remedios CG,Tsang VT,Frigiola A,Kentish JC

Tue Aug 18 00:00:00 UTC 2020

Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement.

Journal of the American Heart Association

Brayson D,Holohan SJ,Bardswell SC,Arno M,Lu H,Jensen HK,Tran PK,Barallobre-Barreiro J,Mayr M,Dos Remedios CG,Tsang VT,Frigiola A,Kentish JC

Tue Aug 18 00:00:00 UTC 2020

生物信息学

蛋白别名: Asporin; asporin (LRR class 1); asporin proteoglycan; FLJ20129; periodontal ligament associated protein 1; Periodontal ligament-associated protein 1; PLAP-1; small leucine-rich protein 1C

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基因别名: ASPN; OS3; PLAP-1; PLAP1; SLRR1C; UNQ215/PRO241

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UniProt ID: (Human) Q9BXN1

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Entrez Gene ID: (Human) 54829

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功能

protein kinase inhibitor activity calcium ion binding collagen binding

参与通路

negative regulation of protein kinase activity cytokine-mediated signaling pathway bone mineralization negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of JAK-STAT cascade negative regulation of tooth mineralization