Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Alomone Labs, LTD
B2 Bradykinin Receptor (BDKRB2) Polyclonal Antibody
FIGURE: 1 / 2
B2 Bradykinin Receptor (BDKRB2) Antibody (ABR-012-200UL) in IHC
Expression ofB2bradykinin receptorin mouse spinal cord - Immunohistochemical staining of mouse spinal cord using Anti-B2Bradykinin Receptor (BDKRB2) Antibody (#ABR-012). A. BKR2 (red) appears in several spinal cord neurons (triangles). B. Parvalbumin (green) appears in neurons. C. Merge of BKR2and parvalbumin shows co-expression in several neurons (triangles) but not all (arrow in C). DAPI is used as the co... View More
Product Details
ABR-012-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GKRFRKKSWEVYQG(C), corresponding to amino acid residues 336-349 of human B2R, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.75 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: B2 bradykinin receptor; B2R; BK-2 receptor; BK-2R; BK-2Rs; bradykinin receptor, beta 2; DKFZp686O088; kinin B2
Gene Aliases: B(2); B2; B2BKR; B2BRA; B2R; BDKRB2; BK-2; BK2; BK2R; BKR2; BRB2
UniProt ID: (Human) P30411, (Mouse) P32299, (Rat) P25023
Entrez Gene ID: (Human) 624, (Mouse) 12062, (Rat) 25245
protease binding
phosphatidylinositol phospholipase C activity
bradykinin receptor activity
protein binding
beta-2 adrenergic receptor binding
type 1 angiotensin receptor binding
protein heterodimerization activity
signal transducer activity
G-protein coupled receptor activity
G-protein coupled receptor
acute inflammatory response to antigenic stimulus
smooth muscle contraction
inflammatory response
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
negative regulation of cell proliferation
response to salt stress
regulation of vasoconstriction
negative regulation of peptidyl-serine phosphorylation
maintenance of blood-brain barrier
vasoconstriction
vasodilation
response to drug
regulation of vascular permeability
negative regulation of blood pressure
arachidonic acid secretion
cellular response to hypoxia
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
response to stress
signal transduction
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
sensory perception of pain
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support