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B3GNT3 Antibody (PA5-100401) in IHC (P)
Immunohistochemistry analysis of B3GNT3 in human liver cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with B3GNT3 polyclonal antibody (Product # PA5-100401) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-100401
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human B3GNT3(Accession Q9Y2A9), corresponding to amino acid residues C303-L353.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2849913
Product Specific Information
Antibody detects endogenous levels of total B3GNT3.
Target Information
This gene encodes a member of the beta-1, 3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase; Beta-1,3-galactosyltransferase 8; Beta-1,3-GalTase 8; beta-1,3-Gn-T3; beta-1,3-N-acetylglucosaminyltransferase 3; beta-1,3-N-acetylglucosaminyltransferase bGnT-3; Beta-3-Gx-T8; beta3GalT8; beta3Gn-T3; BGnT-3; core 1 beta-1,3-N-acetylglucosaminyltransferase; Core 1 extending beta-1,3-N-acetylglucosaminyltransferase; Core1-beta3GlcNAcT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3; putative type II membrane protein; Transmembrane protein 3; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
Gene Aliases: 2210008L19Rik; B3GAL-T8; B3GALT8; B3GN-T3; B3GNT-3; B3GNT3; beta3Gn-T3; HP10328; TMEM3; UNQ637/PRO1266
UniProt ID: (Human) Q9Y2A9, (Mouse) Q5JCS9
Entrez Gene ID: (Human) 10331, (Mouse) 72297
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity
galactosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
glycosyltransferase
Performance Guarantee
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