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B3GNT3 Antibody (PA5-21988) in IHC (P)
B3GNT3 Polyclonal Antibody detects B3GNT3 protein at cytosol on human colon by immunohistochemical analysis. Sample: Paraffin-embedded colon. B3GNT3 Polyclonal Antibody (Product # PA5-21988) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-21988
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 122 and 338 of B3GNT3 (Uniprot ID#Q9Y2A9)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11152536
Product Specific Information
Recommended positive controls: 293T, mouse stomach.
Predicted reactivity: Mouse (81%), Rat (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the beta-1, 3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase; Beta-1,3-galactosyltransferase 8; Beta-1,3-GalTase 8; beta-1,3-Gn-T3; beta-1,3-N-acetylglucosaminyltransferase 3; beta-1,3-N-acetylglucosaminyltransferase bGnT-3; Beta-3-Gx-T8; beta3GalT8; beta3Gn-T3; BGnT-3; core 1 beta-1,3-N-acetylglucosaminyltransferase; Core 1 extending beta-1,3-N-acetylglucosaminyltransferase; Core1-beta3GlcNAcT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3; putative type II membrane protein; Transmembrane protein 3; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
Gene Aliases: 2210008L19Rik; B3GAL-T8; B3GALT8; B3GN-T3; B3GNT-3; B3GNT3; beta3Gn-T3; HP10328; TMEM3; UNQ637/PRO1266
UniProt ID: (Human) Q9Y2A9, (Mouse) Q5JCS9
Entrez Gene ID: (Human) 10331, (Mouse) 72297
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity
galactosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
glycosyltransferase
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