Invitrogen

B4GALT2 Polyclonal Antibody

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B4GALT2 Antibody (PA5-109440) in WB

Western blot analysis of B4GALT2 in extracts of various cell lines. Samples were incubated with B4GALT2 Polyclonal antibody (Product # PA5-109440) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

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产品信息

PA5-109440

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 155-271 of human B4GALT2 (NP_085076.2).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2.01 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.01% thimerosal

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2854851

产品详细信息

Immunogen sequence: PGVLMGGRYT PPDCTPAQTV AVIIPFRHRE HHLRYWLHYL HPILRRQRLR YGVYVINQHG EDTFNRAKLL NVGFLEALKE DAAYDCFIFS DVDLVPMDDR NLYRCGDQPR HFAIAMD

靶标信息

B4GALT2 is one of type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: 4-Gal; b4Gal-T2; Beta-1,4-galactosyltransferase 2; beta-1,4-galactosyltransferase II; Beta-1,4-GalTase 2; beta-4-GalT2; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 2; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; beta4Gal-T2; Lactose synthase A protein; N-acetyllactosamine synthase; Nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2; UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2

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基因别名: B4Gal-T2; B4Gal-T3; B4GALT2; beta4Gal-T2; Ggtb2

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UniProt ID: (Human) O60909, (Mouse) Q9Z2Y2

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Entrez Gene ID: (Human) 8704, (Mouse) 53418, (Rat) 313536

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功能